Tina and her brother Leone live in Venice. Leone works at the Gallerie dell’Accademia and is thrilled because a famous Leonardo da Vinci painting, "Lady with an Ermine" has just arrived at the museum. Tina, however, is anxious: the seasonal acqua alta is rising, and she’s afraid of water. When thieves steal the painting and Leone suddenly disappears, Tina must overcome her fears, track down the stolen artwork, and rescue her brother.